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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1966 1
1975 1
1978 2
1990 2
1993 1
1994 3
1995 1
1996 1
1997 1
1999 2
2003 2
2004 1
2006 1
2010 1
2011 1
2012 1
2014 2
2015 2
2016 4
2017 1
2018 3
2019 5
2020 7
2021 9
2022 10
2023 9
2024 2

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73 results

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Page 1
Dual-Color Fluorescent Timer Enables Detection of Growth-Arrested Pathogenic Bacterium.
Xia A, Han J, Jin Z, Ni L, Yang S, Jin F. Xia A, et al. ACS Infect Dis. 2018 Dec 14;4(12):1666-1670. doi: 10.1021/acsinfecdis.8b00129. Epub 2018 Sep 17. ACS Infect Dis. 2018. PMID: 30215505
Unlike the use of transcriptional reporters to gauge the metabolic activities in cells, here, we fuse two different fluorescent proteins with distinctive maturation rates to construct a timer to directly determine the growth rate of single Pseudomonas aeruginosa cells. We …
Unlike the use of transcriptional reporters to gauge the metabolic activities in cells, here, we fuse two different fluorescent proteins wit …
DUAL-PURPOSE RELAY TIMER.
RICHARDSON J, ULRICH R, WOLFF P. RICHARDSON J, et al. J Exp Anal Behav. 1964 Jan;7(1):123-4. doi: 10.1901/jeab.1964.7-123. J Exp Anal Behav. 1964. PMID: 14120128 Free PMC article. No abstract available.
In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer.
He L, Binari R, Huang J, Falo-Sanjuan J, Perrimon N. He L, et al. Elife. 2019 May 29;8:e46181. doi: 10.7554/eLife.46181. Elife. 2019. PMID: 31140975 Free PMC article.
In addition, by combining a fast-folding destabilized fluorescent protein and a slow-folding long-lived fluorescent protein, we generated a dual-color transcriptional timer that provides spatio-temporal information about signaling pathway activities. Finally, we dem …
In addition, by combining a fast-folding destabilized fluorescent protein and a slow-folding long-lived fluorescent protein, we generated a …
The dual role of complement in cancers, from destroying tumors to promoting tumor development.
Lu P, Ma Y, Wei S, Liang X. Lu P, et al. Cytokine. 2021 Jul;143:155522. doi: 10.1016/j.cyto.2021.155522. Epub 2021 Apr 10. Cytokine. 2021. PMID: 33849765 Review.
In this review, to unravel the complex relationship between complement and tumors, we reviewed the high diversity of complement components in cancer and the heterogeneity of their production and activation pathways. In the tumor microenvironment, complement plays a dual re …
In this review, to unravel the complex relationship between complement and tumors, we reviewed the high diversity of complement components i …
The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer.
Fullstone G, Bauer TL, Guttà C, Salvucci M, Prehn JHM, Rehm M. Fullstone G, et al. Cell Death Differ. 2020 Oct;27(10):2828-2842. doi: 10.1038/s41418-020-0545-9. Epub 2020 Apr 27. Cell Death Differ. 2020. PMID: 32341447 Free PMC article.
Recent findings have shown that autocleavage of PC9 to Caspase 9 (C9) p35/p12 not only permits XIAP-mediated C9 inhibition but also temporally shuts down apoptosome activity, forming a molecular timer. In order to delineate the combined contributions of XIAP and the apopto …
Recent findings have shown that autocleavage of PC9 to Caspase 9 (C9) p35/p12 not only permits XIAP-mediated C9 inhibition but also temporal …
Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized cortically differentiating human pluripotent stem cells.
Peter M, Shipman S, Macklis JD. Peter M, et al. bioRxiv [Preprint]. 2023 Aug 26:2023.08.04.552012. doi: 10.1101/2023.08.04.552012. bioRxiv. 2023. PMID: 37609140 Free PMC article. Preprint.
Toward solving this, we generated and tested a range of knock-in hPSC lines that express five distinct dual FP timer systems or single time-resolved fluorescent timer (FT) molecules, either in 293T cells or in human hPSCs driving expression from the endogenou …
Toward solving this, we generated and tested a range of knock-in hPSC lines that express five distinct dual FP timer systems o …
A chemically encoded timer for dual molecular delivery at tailored ranges and concentrations.
Serra S , Alouane A , Le Saux T , Huvelle S , Plasson R , Schmidt F , Jullien L , Labruère R . Serra S , et al. Chem Commun (Camb). 2018 Jun 14;54(49):6396-6399. doi: 10.1039/c8cc03253j. Chem Commun (Camb). 2018. PMID: 29872786
To address this goal, we exploit a low molecular weight branched self-immolative architecture, which acts as a triggerable chemically encoded timer for autonomous sequential release of two chemicals. Using a light-activated model liberating two distinct fluorophores, we ge …
To address this goal, we exploit a low molecular weight branched self-immolative architecture, which acts as a triggerable chemically encode …
Quantitative and dynamic analysis of PTEN phosphorylation by NMR.
Cordier F, Chaffotte A, Wolff N. Cordier F, et al. Methods. 2015 May;77-78:82-91. doi: 10.1016/j.ymeth.2014.10.007. Epub 2014 Oct 18. Methods. 2015. PMID: 25449899 Review.
The dual lipid and protein phosphatase PTEN is a tumor suppressor controlling key biological processes, such as cell growth, proliferation and neuro-survival. ...In each cascade, the reactions follow an ordered model with a distributive kinetic mechanism. The vision of the …
The dual lipid and protein phosphatase PTEN is a tumor suppressor controlling key biological processes, such as cell growth, prolifer …
HIV-Tocky system to visualize proviral expression dynamics.
Reda O, Monde K, Sugata K, Rahman A, Sakhor W, Rajib SA, Sithi SN, Tan BJY, Niimura K, Motozono C, Maeda K, Ono M, Takeuchi H, Satou Y. Reda O, et al. Commun Biol. 2024 Mar 20;7(1):344. doi: 10.1038/s42003-024-06025-8. Commun Biol. 2024. PMID: 38509308 Free PMC article.
In vitro reporter models so far offered a feasible means to inspect this population, but with limited capabilities to dissect provirus silencing dynamics. Here, we describe a new HIV reporter model, HIV-Timer of cell kinetics and activity (HIV-Tocky) with dual fluor …
In vitro reporter models so far offered a feasible means to inspect this population, but with limited capabilities to dissect provirus silen …
Accurate activity determination of a californium neutron source.
Stonaha PJ, Harper C, Tan C, Urban-Klaehn J, Taylor CN, Forest T, Dale D. Stonaha PJ, et al. Appl Radiat Isot. 2023 Apr;194:110712. doi: 10.1016/j.apradiso.2023.110712. Epub 2023 Feb 3. Appl Radiat Isot. 2023. PMID: 36764223
We identify two unique types of false trigger events in a leading-edge discriminator and show how a dual timer module can be used to produce a veto window to exclude these events. ...
We identify two unique types of false trigger events in a leading-edge discriminator and show how a dual timer module can be u …
73 results